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150+ doctors have already invested

Invest in a Faster, Less Painful Dental Anesthetic in a $2.2 B Annual Market

* Additional patent-pending medical vial technology for potential use in dermatology, emergency medicine, and more

The Market

$2.2 Billion Annual Market Opportunity6

* Represents dental anesthetic market only, does not include additional medical vial markets (e.g. dermatology, plastic surgery)

744 Million Units per Year in Serviceable Available Markets

Current usage in our targeted dental markets—North America, Western Europe, Japan, and South Korea—is 744 million units. Total worldwide is 1.9 billion units1.

$220 Million Estimated Revenue for Each 10% of Market Share

BPI has a target average wholesale price of ~$4.00 (est.) per cartridge.

Additional Medical Market Potential

BPI’s patent-pending medical vial technology7 may allow later entry into dermatology, plastic surgery, emergency medicine, interventional radiology, and podiatry markets10.

technology investment background

The Research

Strong Positive Reaction from Dentists

See what dentists (our end users) think about our patent-protected technology7,8 and having pH-balanced anesthetic available to use immediately for their patients (e.g. no manual mixing)

diverse dentists smiling
Say they are likely to use Libracaine8, when available
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Think using Libracaine would increase referrals8
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Say they are likely to feature Libracaine on their website and in their marketing materials8
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A pH-balanced anesthetic in a standard dental cartridge will be a game changer.

- Jason Goodchild, DMD

Dr. Goodchild holds academic appointments at the University of Pennsylvania School of Dental Medicine, Rutgers School of Dental Medicine, and Creighton University School of Dentistry. He has authored more than 50 research papers on the subject of dental pain management.

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A pH-balanced anesthetic in a standard dental cartridge will be a game changer.

- Jason Goodchild, DMD

Dr. Goodchild holds academic appointments at the University of Pennsylvania School of Dental Medicine, Rutgers School of Dental Medicine, and Creighton University School of Dentistry. He has authored more than 50 research papers on the subject of dental pain management.

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The innovative cartridges and their contents answer the pharmacological challenges with such elegance.

- Arthur DiMarco, DMD

Dr. DiMarco is the co-author of Local Anesthesia for Dental Professionals,a leading textbook for dental programs.  He is a professor at Eastern Washington University.

Read recent press about Balanced Pharma's patented dental technology in the following publications:
Company News

Balanced Pharma Announces the First 75 Members of its Clinical Advisory Board

Balanced Pharma's Clinical Advisory Board includes practicing clinicians across multiple specialties that use local anesthetic, including dentistry, dermatology, interventional radiology, plastic surgery, and emergency medicine.

Mamta Patel
Wenhong Peng
Robert Chen

A Problem Worth Solving

Dental Injections are Unnecessarily
Painful, Slow-Acting, and Unreliable

More than half of patients think the injection is the worst part of the dental experience. 90% of dentists want an improved dental anesthetic2,3.

female patient, holding jaw after painful dental injection

Each Year, Patients Suffer Nearly 2 Billion Dental Injections

These injections are stressful for both patients and dentists, and for good reason:
  • The acid preservative in local anesthetic drugs causes pain during injection and a delayed anesthetic effect.
  • Local anesthetic pH can be 25,000 times more acidic than human tissue.
  • For dentists, this means uncomfortable patients, wasted time, and wasted money.

Painful injection

Long wait time

20% avg. failure rate

Time & money wasted

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Dentists report that current dental injections have a 20% average failure rate4
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58% of patients believe the injection is the worst part of the dental experience1
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90% of dentists want an improved dental anesthetic3

The Solution

The First and Only pH-Balanced
Dental Anesthetic

Our patent-protected technology7 can deliver a less painful, faster-acting, and more reliable5 dental anesthetic with the convenience of the equipment clinicians already use and trust.

Introducing Libracaine® Dental9

The First and Only pH-Balanced Dental Anesthetic
The Convenience of a Standard Dental Cartridge

The Technology

Our Patent-Protected Libracaine® Cartridge

Because Libracaine will be supplied in a standard dental cartridge, dentists can seamlessly replace their current anesthetic with the new pH-balanced Libracaine Dental anesthetic9.

Founder's Story

A Dentist on a Mission to Improve Patient Comfort

"We want to provide the best possible experience for patients."

- Scott Keadle, DDS | CEO, Balanced Pharma

Meeting the Need for Less Painful, Faster-Acting Dental Injections

Dr. Scott Keadle, a dentist for over 30 years, experienced firsthand the limitations of current dental anesthetic drugs and their inability to provide a fast-acting, reliable, and painless injection.

He wanted a better anesthetic for his patients: Less injection pain, less waiting time, and more reliability.

A New Anesthetic. Created for Clinicians, by Clinicians.

Dr. Keadle invented patented technology7 to enable pH-balanced versions of the most common local anesthetics, using a standard syringe and protocol.  He then presented the opportunity to a group of dentists who invested over $1 million to help found Balanced Pharma Incorporated (BPI).

Now he leads a team of industry experts who are committed to bringing the first-ever pH-balanced dental anesthetic to market.

Dr. Keadle and Dr. Chu walking in office, talking
young girl smiling with female dentist, holding up

Invest in a Faster, Less Painful Dental Anesthetic

Balanced Pharma is pioneering the movement toward less painful, faster-acting, more reliable dental injections.

Become an investor today!

The Team

Balanced Pharma Team

Our growing team is dedicated to excellence in our mission to improve patient comfort.

bpi_scott_keadle-web

John S. Keadle, DDS

Chairman and CEO

Founder and CEO at Balanced Pharma, 30+ years as a dentist, practice owner and business executive

John Selig

John Selig

Board Director

Managing Partner at WaveEdge Capital, 25+ years in life science investment banking and M&A practice

Mark Sebree

Mark Sebree

Board Director,
Chief Development Officer

Former CEO, Becton Dickinson Rx; 35+ years in strategy, acquisitions, and operations in the pharma industry

Eric Sherb

Eric Sherb

Chief Financial Officer

13 years experience in accounting advisory, auditing, and M&A; extensive experience in financial reporting

Jason Suggs

Jason Suggs

Chief Communications Officer

CEO at Orange Reef, 20+ years in brand strategy, communications, and technology

Nita Patel

Nita U. Patel, Ph.D.

Senior Advisor—CMC

SVP, Global Reg. Issues and Head of CMC, at ProPharma Group; 30+ years of R&D and pharmaceutical industry experience

Steve Jensen

Steve Jensen

Senior Advisor—Regulatory

EVP, Head of U.S. Regulatory Sciences, at ProPharma Group; 22+ years of pharmaceutical industry experience

Alex Sadusky

Alex Sadusky

Senior Advisor—Commercial

CEO, TruBlu Dental; Former Dentsply Sirona Senior Executive; Former Senior External Advisor, McKinsey & Co. Pharma & Med Products Division

Sara Hanks

Sara Hanks, Esq.

Securities Counsel

CEO, CrowdCheck Law Firm

Byron Kirkland

Byron Kirkland, Esq.

Corporate Counsel

Managing Partner, Smith Anderson Law Firm

Scientific Advisory Board

Bishr Al Dabagh

Bishr Al-Dabagh, MD, MBA, FAAD, FACMS

Scientific Advisor

Board-certified dermatologist (American Board of Dermatology), fellowship-trained dermatologic surgeon (American College of Mohs Surgery), and a fellow of the American Academy of Dermatology (AAD). Dr. Al-Dabagh has published over 20 peer-reviewed articles and book chapters.

Larina Chu, DDS, M-PA, CLS

Larina Chu, DDS, M-PA, CLS

Scientific Advisor

Dentist anesthesiologist serving the greater Hesperia, California area. Dr. Chu is a professional member of the American Board of Dental Anesthesiologists, the American Dental Association, the California Dental Association and the Tri-County Dental Society.

Mark Donaldson, Pharm D.

Mark Donaldson, Pharm.D.

Scientific Advisor

Associate Principal at Vizient Pharmacy Advisory Solutions, 17+ years as a recognized expert in dental pharmacology, He holds academic appointments at the University of Montana and the Oregon Health & Sciences University and serves on the editorial board of the Journal of the American Dental Association.  

Jay Reznik, DMD, MD

Jay B. Reznick, DMD, MD

Scientific Advisor

Director of the Southern California Center for Oral and Facial Surgery in Tarzana, California; Diplomate of the American Board of Oral and Maxillofacial Surgery; the first specialist in the U.S. to integrate CBCT and CAD/CAM in his practice; has been published extensively in dental and medical literature

John Robertson, DMD

John B. Roberson, DMD

Scientific Advisor

Oral & Maxillofacial Surgeon; CEO and Co-Founder of AAFDO (Accreditation Association For Dental Offices); CEO and Co-founder. of the Institute of Medical Emergency Preparedness; author and lecturer; selected as a CE Leader for Dentistry Today for 10 consecutive years.

Clinical Advisory Board

Balanced Pharma’s Clinical Advisory Board includes over 75 practicing clinicians across multiple specialties that use local anesthetic.

Mamta Patel

Mamta Patel

DDS

Dentist; Owner, Stamford Dental Spa; University of Connecticut; Licensed in CT, NY

bpi_cab_marcus_johnson

Marcus Johnson

DDS, MSD

Endodontist; Lecturer, Teacher, Interfaith Hospital; NYU Dental School

Wenhong Peng

Wenhong Peng

DDS, MPH, MBA

Dentist; Owner, Peng Dental Health; Harvard School of Public Health

bpi_cab_elaine_vowell_closeup3

Elaine Vowell

DDS, FAGD

Dentist; Founder, Your Best Shot; Creighton University School of Dentistry

bpi_cab_gildo_corradi

Gildo Corradi

DDS

Dentist; Owner, Midtown Manhattan Dental Arts; Lecturer, Anesthesia; Residency, Mount Sinai

bpi_cab_nawaf_aslam-pervez

Nawaf Aslam-Pervez

MD, DDS, MRCS, FRCD

Oral & Maxillofacial Surgeon; Former Assistant Professor, Department of Surgery, Mayo Clinic; Trinity College of Dublin, Royal College of Surgeons

bpi_cab_traci_mccormick

Traci McCormick

MD

Radiation Oncologist; CEO and Medical Director, Precision MD Wellness; Residency, Indiana University

Robert Chen

Robert Chen

MD, FAAEM

Emergency Physician; Medical Director; St. Louis University

bpi_cab_ethan_chase

Ethan Chase

DMD, CAGD

Dentist; Clinical Lecturer, Boston University Goldman School of Dental Medicine

bpi_cab_pedram_mastour

Pedram Mastour

DDS

Dentist; Clinical Assistant Professor, Division IV, The Herman Ostrow School of Dentistry, USC

bpi_cab_nancy_dulin

Nancy Dulin

MD

Anesthesiologist; University of Alabama School of Medicine; Wake Forest Baptist Medical Center

bpi_cab_samer_elbatanouny

Samer Elbatanouny

BDS, DDS, FAGD, MHA, FADIA, MIDIA

Dentist; Mastership, International Dental Implant Association

View additional members of the Clinical Advisory Board at BalancedPharma.com.

THIS WEBSITE MAY CONTAIN FORWARD-LOOKING STATEMENTS AND INFORMATION RELATING TO, AMONG OTHER THINGS, THE COMPANY, ITS BUSINESS PLAN AND STRATEGY, AND ITS INDUSTRY.  THESE FORWARD-LOOKING STATEMENTS ARE BASED ON THE BELIEFS OF, ASSUMPTIONS MADE BY, AND INFORMATION CURRENTLY AVAILABLE TO THE COMPANY’S MANAGEMENT.  WHEN USED IN THE OFFERING MATERIALS, THE WORDS “ESTIMATE,” “PROJECT,” “BELIEVE,” “ANTICIPATE,” “INTEND,” “EXPECT” AND SIMILAR EXPRESSIONS ARE INTENDED TO IDENTIFY FORWARD-LOOKING STATEMENTS, WHICH CONSTITUTE FORWARD LOOKING STATEMENTS. THESE STATEMENTS REFLECT MANAGEMENT’S CURRENT VIEWS WITH RESPECT TO FUTURE EVENTS AND ARE SUBJECT TO RISKS AND UNCERTAINTIES THAT COULD CAUSE THE COMPANY’S ACTUAL RESULTS TO DIFFER MATERIALLY FROM THOSE CONTAINED IN THE FORWARD-LOOKING STATEMENTS.  INVESTORS ARE CAUTIONED NOT TO PLACE UNDUE RELIANCE ON THESE FORWARD-LOOKING STATEMENTS, WHICH SPEAK ONLY AS OF THE DATE ON WHICH THEY ARE MADE.  THE COMPANY DOES NOT UNDERTAKE ANY OBLIGATION TO REVISE OR UPDATE THESE FORWARD-LOOKING STATEMENTS TO REFLECT EVENTS OR CIRCUMSTANCES AFTER SUCH DATE OR TO REFLECT THE OCCURRENCE OF UNANTICIPATED EVENTS.

(1) “58% OF PATIENTS BELIEVE THE INJECTION IS THE WORST PART OF THE DENTAL EXPERIENCE,” OLSON RESEARCH GROUP, “PATIENT DENTAL CARE STUDY QUANTITATIVE REPORT, CONDUCTED FOR BALANCED PHARMA, MAY 7, 2021,” FIELDING: MARCH 30–APRIL 23, 2021, TOTAL SAMPLE SIZE: N=140 (INCLUDES 40 PARENTS/CAREGIVERS)

(2) “WHAT PATIENTS WANT: A LESS-PAINFUL DENTAL INJECTION: 86%,” OLSON RESEARCH GROUP, “PATIENT DENTAL CARE STUDY QUANTITATIVE REPORT, CONDUCTED FOR BALANCED PHARMA, MAY 7, 2021,” FIELDING: MARCH 30–APRIL 23, 2021, TOTAL SAMPLE SIZE: N=140 (INCLUDES 40 PARENTS/CAREGIVERS)

(3) “OVER 90% OF DENTISTS REPORT A DESIRE FOR CURRENT ANESTHETICS TO BE MORE RELIABLE, LESS PAINFUL, OR FASTER ACTING,” OLSON RESEARCH GROUP, “DENTIST QUANTITATIVE REPORT, CONDUCTED FOR BALANCED PHARMA, AUGUST 13, 2021,” FIELDING: JUNE 18–JULY 19, 2021, TOTAL SAMPLE SIZE: N=181;

(4) “DENTISTS REPORT AN INITIAL ANESTHETIC FAILURE RATE OF 20%,” OLSON RESEARCH GROUP, “DENTIST QUANTITATIVE REPORT, CONDUCTED FOR BALANCED PHARMA, AUGUST 13, 2021,” FIELDING: JUNE 18–JULY 19, 2021, TOTAL SAMPLE SIZE: N=181

(5) 2018 META-ANALYSIS: SIGNIFICANTLY DECREASED ONSET TIME AND INJECTION PAIN; GUO ET AL FROM UNIVERSITY OF SOUTHERN CALIFORNIA SCHOOL OF DENTISTRY CONCLUDED: “BUFFERED LIDOCAINE SIGNIFICANTLY DECREASED ONSET TIME AND INJECTION PAIN (VAS) COMPARED WITH NON-BUFFERED LIDOCAINE IN INFERIOR ALVEOLAR NERVE BLOCK.”; 2017 CLINICAL STUDY: REDUCES THE PAIN ON INJECTION; PHERO ET AL FROM UNIVERSITY OF NORTH CAROLINA SCHOOL OF DENTISTRY CONCLUDED: “BUFFERED LIDOCAINE REDUCES THE PAIN ON INJECTION WITH A MAXILLARY FIELD BLOCK AND RESULTS IN SIMILAR LENGTHS OF PULPAL ANESTHESIA AS NON-BUFFERED 2% LIDOCAINE.” 2017 CLINICAL STUDY: LOWER PAIN ON INJECTIONS. WARREN ET AL FROM UNIVERSITY OF NORTH CAROLINA SCHOOL OF DENTISTRY CONCLUDED: “AFTER MANDIBULAR NERVE BLOCK, BUFFERED 1% LIDOCAINE CAN PRODUCE SIMILAR DURATION OF PULPAL ANESTHESIA AS NON-BUFFERED 2% LIDOCAINE AND LOWER PAIN ON INJECTIONS.”; 2019 META-ANALYSIS: 2.29 TIMES MORE RELIABLE IN INFLAMED TEETH; KATTAN ET AL FROM UNIVERSITY OF PENNSYLVANIA SCHOOL OF DENTISTRY CONCLUDED: “BUFFERED LOCAL ANESTHETICS HAVE 2.29 TIMES GREATER LIKELIHOOD OF ACHIEVING SUCCESSFUL ANESTHESIA [IN PULPALLY INVOLVED TEETH].”

(6) SDM NORTHCOAST, LLC REPORT, “INJECTABLE CARPULES MARKET SIZE ANALYSIS, UNITED STATES, CANADA, MEXICO, 2019 UNITS”, JULY 15, 2021; KEY-STONE RESEARCH, “EUROPEAN LOCAL ANESTHETICS MARKET SURVEY,” SEPTEMBER 20, 2021; BALANCED PHARMA INTERNAL ESTIMATES

(7) BPI OWNS THE FOLLOWING GRANTED PATENTS AND PENDING PATENT APPLICATIONS: U.S. PATENT NO. 11,305,064 (ISSUED APRIL 19TH, 2022); U.S. APPLICATION NO. 17/722,016; INTERNATIONAL PCT APPLICATION NO. PCT/IB2018/052598; CANADIAN APPLICATION NO. 3,111,347 (CANADIAN NATIONAL PHASE OF PCT/IB2018/052598); EUROPEAN APPLICATION NO. 18897951.2 (EUROPEAN REGIONAL PHASE OF PCT/IB2018/052598); JAPANESE APPLICATION NO. 2020-556351 (JAPANESE NATIONAL PHASE OF PCT/IB2018/052598); KOREAN APPLICATION NO. 10-2020-7021685 (REPUBLIC OF KOREA NATIONAL PHASE OF PCT/IB2018/052598); U.S. APPLICATION NO. 16/655,362; U.S. APPLICATION NO. 63/233,879; BPI ALSO OWNS ONE TRADEMARK APPLICATION, U.S. APPLICATION NO. 88/198,808, PENDING FOR THE LIBRACAINE MARK.

(8) OLSON RESEARCH GROUP, “U.S. DENTIST QUANTITATIVE REPORT, CONDUCTED FOR BALANCED PHARMA, AUGUST 13TH, 2021,” TOTA SAMPLE SIZE: 181 DENTISTS; KEY-STONE RESEARCH, “EUROPEAN LOCAL ANESTHETICS MARKET SURVEY, CONDUCTED FOR BALANCED PHARMA, SEPTEMBER 20, 2021,” TOTAL SAMPLE SIZE: 433 DENTISTS

(9) LIBRACAINE HAS NOT YET BEEN APPROVED BY FDA AND IS NOT AVAILABLE FOR SALE.

(10) BPI HAS NOT YET BEGUN TRIALS TO DETERMINE WHETHER ITS TECHNOLOGY CAN ADAPT TO DERMATOLOGY, PLASTIC SURGERY, EMERGENCY MEDICINE, INTERVENTIONAL RADIOLOGY, AND PODIATRY.

Balanced Pharma, Inc.
18204 Mainsail Pointe
Cornelius, NC 28031

investor@balancedpharma.com
(980) 939-7573

Balanced Pharma, Inc.
18204 Mainsail Pointe
Cornelius, NC 28031

investor@balancedpharma.com
(980) 939-7573

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